Best NAD+ Therapy Providers of 2026
NAD+ in 2 Formats, Starting At Just $99
NAD+ Any Format, $149/mo
NAD+ Injections From $99
05
DirectMeds
Very Good
Physician-Backed NAD+, Shipped
- Physician-reviewed NAD+ prescriptions with dosage guidance built into every plan
- All-inclusive pricing covers medication, consultation, and 2-day shipping, no hidden fees
- Backed by LegitScript certification and a 4.6-star Trustpilot rating from over 13,000 customers
10
Wellmedr
Fair
Same-Day NAD+, No Hidden Fees
- Licensed US providers review every intake and write same-day prescriptions when appropriate
- Flat, transparent pricing means your cost per dose never changes as treatment continues
- No membership required, cancel anytime, with free 1–2 day shipping from US pharmacies
11
Embody
Fair
Flexible NAD+, No Membership
- Choose between NAD+ injections or nasal spray based on what fits your routine
- 100% online medical visit, prescription, and telemedicine consultation are included in one upfront price
- No membership requirement means you can pause or cancel your plan at any time
17
Enhance MD
Fair
Clinical-Level NAD+, Personalized
- NAD+ restored to clinical levels, personalized to your energy, recovery, and aging goals
- Every protocol reviewed by board-certified providers and overseen by an Independent Medical Commission
- 90-day money-back guarantee, no questions asked, plus free 1–2 day shipping
21
Taurus
Fair
NAD+ From $79, Then $179 a Month
- NAD+ shots priced as low as $10.75 per shot, homekit included
- Rated on Trustpilot by 721+ customers, though recent reviews flag billing issues
- A verified review reports an unauthorized charge after cancellation — confirm cancellation terms before you subscribe
Best Overall Pick
Which NAD+ Protocol Is Right for Me?
Every provider on this page dispenses the same coenzyme. What differs is the route it takes, what the price looks like after the first month, and how much clinician time comes with it. Settling the format first usually narrows the list to three or four. Whether NAD+ is appropriate for you is a question for a licensed clinician who has your full medical history.
Subcutaneous injection
A small self-administered injection, usually weekly, delivering NAD+ into subcutaneous tissue rather than through the digestive tract. It is the most common at-home format and the one most programmes are built around.
On this page: Remote Pharmacy from $99, bmiMD from $89/month, System at $89, DirectMeds at $99 for the first month, and the default format at most providers ranked here.
Nasal spray
Needle-free and dosed daily instead of weekly. It suits anyone who will not self-inject, and it is generally the cheapest way into a programme — which also makes it the format where the introductory price is furthest from the ongoing one.
On this page: Telos from $49 on a 12-month plan, System at $69 for the first month, and Pallas Health at $79 first month, $189/month average.
Choose-your-format plans
One price, several routes. The decision becomes about what you are comfortable using rather than what you can afford, and switching format later does not mean switching provider.
On this page: BettermeRx runs injection or nasal spray from $99/month, He & She MD prices injection, cream and nasal identically at $149/month, and Embody and Pallas Health each offer injection or nasal.
Physician-designed protocols
A clinician sets the dose against your history and revisits it as you go, rather than shipping a standard plan. The price is higher because the clinical time is inside it.
On this page: Enhanced.com from $129/month, Fridays from $179/month, RenuviaRX from $179, and Enhance MD at the personalised end.
Oral precursors
NMN and NR are precursors — building blocks the body converts toward NAD+ — rather than the coenzyme itself. The most convenient route and the least direct one, which is the trade being made.
On this page: Lttl prices oral NAD+ at the same rate whatever the dose; several ranked providers offer an oral option alongside injection.
Clinic IV infusion
The original delivery route, given in a clinic over several hours. It is not a telehealth product and no provider on this page ships it — it is listed here because it is what most people have heard of, at $300–$1,000+ per session.
On this page: Not offered by any provider ranked on this page; every programme here is at-home.
What NAD+ therapy is not
NAD+ is a wellness protocol, not a treatment for any diagnosed condition, and compounded NAD+ has not been evaluated by the FDA for safety or effectiveness. No provider on this page — and no page on this site — can tell you what it will do for you. Disclose your full medical history and every medication and supplement you take at intake, and speak to your own doctor before adding it to an existing protocol.
How We Evaluate NAD+ Providers
Our comparison is a documentary review of what each provider publishes, checked against its own site. We do not run clinical trials, we do not test medication, and we do not collect patient outcome data — so you will not find efficacy scores, success rates or survey results anywhere on this page.
Clinician oversight
Whether a licensed prescriber genuinely reviews your intake, and whether you can reach one again to change a dose rather than only at sign-up.
Pharmacy sourcing
Whether the compounding pharmacy is named and state-licensed. Compounded NAD+ is only as good as the facility preparing it, and the better programmes say who that is.
Price after the first month
The introductory figure and the ongoing one, side by side. A $79 first month against $189/month average is a different offer from a flat $99, and only one of those is what you pay in month four.
Format options
Injection, nasal spray, cream or oral — and whether the plan price changes when the format does.
What is bundled
Consultation, shipping, follow-up and dose adjustments inside the monthly price, or billed as extras once you are enrolled.
Commitment and exit
Plan length, whether a membership fee sits on top of the medication, and how cancellation actually works.
Editorial scores and reader vote counts shown on the cards reflect ExploreTreatments’ own assessment and the votes cast on our NAD+ pages. They are not clinical ratings, and they are not a measure of medical effectiveness. Provider details change frequently — always confirm current pricing and terms on the provider’s own site before you buy.
The Complete Guide to NAD+ Therapy in 2026
What NAD+ is
NAD+ — nicotinamide adenine dinucleotide — is a coenzyme found in every living cell. The NIH Office of Dietary Supplements describes it as one of the two coenzyme forms the body makes from niacin, taking part in the reduction and oxidation reactions that run cellular metabolism. It is not a hormone and not a drug in its own right; it is a molecule your cells already use constantly, and the concentration of it falls as people age.
That decline is the whole basis of the category. NAD+ programmes supply either the coenzyme or a precursor to it, under clinician supervision, on the reasoning that restoring what age depletes is worth doing. What that produces for any individual is not something this page will claim — the honest framing is that you are buying a supervised protocol, and the evidence base is still developing.
Injection, nasal and oral routes compared
Format is the first decision, and it changes both the price and the daily routine more than the choice of provider does.
| Route | Cadence | Where | What to know |
|---|---|---|---|
| Subcutaneous injection | Usually weekly, self-administered | At home | The most common telehealth format; bypasses the digestive tract |
| Nasal spray | Daily | At home | Needle-free; the lowest entry prices on this page |
| Topical cream | Daily | At home | Offered by a small number of providers, usually at the same plan price |
| Oral precursor (NMN / NR) | Daily | At home | Supplies a precursor rather than NAD+ itself — the least direct route |
| IV infusion | Per session, several hours | Clinic only | Not a telehealth product; $300–$1,000+ per session |
If you already know which route you want, our injection provider ranking and nasal spray ranking filter this list to that format alone.
NAD+ vs NMN and NR
NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are precursors: molecules the body converts along the pathway toward NAD+. Programmes that dispense NAD+ itself skip that conversion step, which is the argument for injection and nasal delivery over oral capsules. Precursors are cheaper, easier to take and available without a prescription — a genuinely different product, not a weaker version of the same one. Our NAD+ vs NMN vs NR guide covers the distinction properly.
What separates a good programme from a cheap one
Four things, all visible before you pay. A low headline price attached to none of them is not a saving:
- A licensed clinician reviews your intake, and is reachable again when a dose needs changing.
- The compounding pharmacy is named and state-licensed — compounded NAD+ is only as good as the facility preparing it.
- The consultation, shipping and follow-up sit inside the monthly price rather than arriving as extras.
- The ongoing price is published as plainly as the introductory one.
What NAD+ therapy costs online
At-home programmes on this page start between $49 and $99 for a first month and settle roughly between $99 and $250/month. Nasal sprays anchor the low end — Telos publishes from $49 on a 12-month plan and System from $69 — injections sit in the middle around $89 to $149, and physician-designed protocols run from $179 upward. Clinic IV infusion, which nobody here ships, is $300–$1,000+ per session.
The number that misleads most often is the first month. DirectMeds is $99 for month one and $199/month after; Pallas Health publishes $79 for its nasal spray against a $189/month average; Wellorithm is $150 then around $200. Compare the figure you will pay in month four, and check whether a membership fee sits on top of the medication — several providers here explicitly do not charge one, which is worth something. Our NAD+ cost checklist runs the same arithmetic provider by provider.
Compounded NAD+ and the FDA
Injectable and nasal NAD+ are compounded preparations: made by a licensed pharmacy against an individual prescription rather than manufactured as an approved finished product. As the FDA explains, compounded drugs are not FDA-approved and are not reviewed for safety or effectiveness before they reach patients. That is not a reason to dismiss the category — it is the reason the prescriber and the pharmacy are the two things to verify, and why every provider ranked here routes your intake through a licensed clinician before anything ships.
How the top-ranked providers compare
BettermeRx takes the top spot on price and risk: injection or needle-free nasal spray from $99/month, with MD review and a money-back guarantee, which makes it the least committing way into the category. He & She MD prices injection, cream and nasal spray identically at $149/month on a 12-month supply, so the format decision is about comfort rather than cost. Remote Pharmacy is the straightforward value entry at $99 with few upsells, and Enhanced.com sits fourth on clinical depth, from $129/month for a personalised protocol.
Below those, DirectMeds runs $99 for the first month then $199 with 1–2 day delivery, bmiMD is the lowest-priced injection programme from $89/month, and Willow charges a flat $199/month with HSA/FSA eligibility. If you are building a wider protocol, our sermorelin provider comparison and glutathione comparison cover the two therapies NAD+ is most often paired with.
Before you start treatment
Compounded NAD+ requires a valid prescription from a licensed clinician and has not been evaluated by the FDA for safety or effectiveness. It is a wellness protocol rather than a treatment for a diagnosed condition. Tell your prescriber about every medication and supplement you take, disclose any history of cardiovascular or liver disease, and raise it with your own doctor if you are pregnant, breastfeeding or managing a chronic condition.
More NAD+ guides
- NAD+ Therapy Cost Checklist Before You Enroll
- What Is NAD+ Therapy? A Plain-Language Overview
- NAD+ vs NMN vs NR: Which Form Should You Take?
- NAD+ Therapy Benefits: What the Evidence Actually Shows
- NAD+ Therapy Side Effects: What to Expect by Delivery Method
- NAD+ Therapy for Longevity: An Evidence-Based Assessment
NAD+ Therapy FAQs
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Medical Disclaimer: The content on this site is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider for medical questions, treatment decisions, or emergency care. Do not disregard professional medical advice or delay seeking it based on information found here.