NAD+ Therapy ComparisonExpert analysis updated June 2026

DirectMeds vs Sprout Health: NAD+ Injection Comparison (2026)

DirectMeds and Sprout Health are two of the most pricing-transparent NAD+ injection programs in the market. DirectMeds starts at $99 for the first month (500mg) and renews at $199, with no automatic billing and manual reordering. Sprout Health is fully disclosed at $149 for the first month and $240 every four weeks for 1,000mg, with a full home kit and free shipping included.

Our Verdict

DirectMeds is the stronger pick for most readers: a lower $99 first month, two dose options, no automatic billing, and a very large public review base. Sprout Health appeals to readers who want the most complete upfront disclosure of dose, renewal, and included kit, and who are comfortable with its higher $240 four-week renewal.

Side-by-Side Feature Comparison

Feature	DirectMeds	Sprout Health	Winner
First-Month Price	$99 first month (500mg)	$149 first month	DirectMeds
Renewal Price	$199/mo (500mg) / $249 (1,000mg)	$240 every 4 weeks	DirectMeds
Billing Model	No automatic billing, manual reorder	Subscription with auto-renewal	DirectMeds
Dose Options	500mg and 1,000mg	1,000mg only	DirectMeds
Delivery Format	Injection only	Injection only	Tie
Shipping	Fast shipping included	Free shipping included	Tie
Public Reviews	4.6/5 (10,155 on Trustpilot)	3.4/5 (94 on Trustpilot)	DirectMeds
Included Care	All-inclusive care and supplies	Consultation and full home injection kit	Tie

Pros and Cons

DirectMeds

Pros

Lower $99 first month (500mg)
Two dose options: 500mg and 1,000mg
No automatic billing, you reorder manually
Very large positive review base (4.6/5, 10,155 reviews)
All-inclusive care and fast shipping

Cons

Injection-only, no nasal or oral format
1,000mg renewal reaches $249

Best For

Readers who want exact pricing, two dose options, and control over reordering with no automatic billing.

Read DirectMeds Review

Sprout Health

Pros

Exact dose, introductory price, and renewal are all public
Consultation, full home injection kit, and free shipping included
Clear cancellation and auto-renewal terms
1,000mg dose disclosed upfront

Cons

$240 every four weeks is a relatively high renewal
Injection is the only public format
Small public review base (94 reviews)

Best For

Readers who want the most complete upfront disclosure of dose, renewal, and included kit, and accept a higher four-week renewal.

Read Sprout Health Review

Frequently Asked Questions: DirectMeds vs Sprout Health

DirectMeds is cheaper to start at $99 for the first month (500mg) versus $149 at Sprout Health. On renewal, DirectMeds is $199/month for 500mg ($249 for 1,000mg), while Sprout Health is $240 every four weeks for 1,000mg. Always weigh the first-month price against the renewal.

DirectMeds does not use automatic billing, you reorder manually when you choose. Sprout Health uses a subscription with auto-renewal, though it discloses its cancellation and renewal terms clearly upfront.

Sprout Health offers a 1,000mg injection. DirectMeds offers both 500mg and 1,000mg options. Both are injection-only programs with no nasal or oral format.

Full Review

DirectMeds

Full Review

Sprout Health

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Editorial Standards: Independent research · Evidence-based analysis · Transparent methodology · 2026