Trimi Review 2026: Compounded Semaglutide From $99/Month & Tirzepatide From $125/Month
By Charly P. · Published June 20, 2026 · 8 min read
Quick Verdict
Trimi offers compounded semaglutide from $99/month and tirzepatide from $125/month — but read those as the longer-term-plan rates, not month-one prices, because the distinction is the whole game here. The company keeps things deliberately plain: simple pricing, online clinician evaluations, free overnight shipping, nationwide availability. Nothing exotic, which after enough of these reviews I've come to see as a quiet point in a platform's favor.
The detail actually worth caring about is the flat-rate model. Where many competitors quietly raise your bill as your dose escalates, Trimi holds it steady — and since GLP-1 doses almost always climb over time, that's the feature that protects you at exactly the moment you're most locked in.
Overall Rating: ★★★★☆ (4.6/5)
| Affordability | 4.9/5 |
|---|---|
| Ease of Signup | 4.8/5 |
| Pricing Transparency | 4.7/5 |
| Shipping & Convenience | 4.8/5 |
| Clinical Support | 4.5/5 |
| Overall Value | 4.6/5 |
What Is Trimi?
Trimi is a fully online weight loss platform that connects patients with licensed U.S. clinicians for GLP-1-based treatment programs. Patients complete an online intake assessment, receive provider review, and if prescribed, medications are shipped directly to their home.
The platform currently focuses on two primary compounded programs: compounded semaglutide and compounded tirzepatide.
Compounded Semaglutide — Starting at $99/Month
Best for budget-conscious patients, first-time GLP-1 users, and long-term weight management.
- ✓GLP-1 receptor agonist
- ✓Appetite suppression support
- ✓Improved fullness
- ✓Once-weekly injections
Compounded Tirzepatide — Starting at $125/Month
Best for patients seeking higher average weight loss outcomes.
- ✓Dual GIP + GLP-1 pathway support
- ✓Once-weekly administration
Trimi references clinical averages of up to 16% weight loss with semaglutide and up to 22% with tirzepatide, though individual results vary significantly.
Pricing Breakdown
One interesting aspect is the discounted pricing structure based on commitment length. The longer the plan, the lower the effective monthly cost.
Semaglutide
| Plan | Price | |
|---|---|---|
| Annual | $99/month | |
| Bi-Annual | $120/month | |
| Quarterly | $145/month | |
| Monthly | $175/month |
Tirzepatide
| Plan | Price | |
|---|---|---|
| Annual | $125/month | |
| 6 Months | $175/month | |
| Quarterly | $199/month | |
| Monthly | $235/month |
Tirzepatide starts at $125/month on the annual plan and $235/month on the monthly plan. As with semaglutide, the longer the commitment, the lower the effective monthly cost.
According to Trimi, plans include:
- ✓Medication
- ✓Injection supplies
- ✓Provider oversight
- ✓Free overnight shipping
- ✓Ongoing portal access
- ✓Support messaging
How Trimi Works
- 1.Complete an Online Visit
Fill out a medical questionnaire about your current weight, medical history, previous weight loss attempts, and treatment goals.
- 2.Provider Review
A licensed medical provider reviews eligibility and creates a personalized treatment plan.
- 3.Receive Medication
If prescribed, medication ships directly to your home with overnight shipping included. Patients receive ongoing access through an online portal. The entire process is virtual.
What We Like
- ✓Competitive entry pricing — annual semaglutide pricing at $99/month is among the more affordable offerings in today’s telehealth GLP-1 market
- ✓Flat pricing model — Trimi advertises consistent pricing regardless of dose adjustments, while many providers increase costs as doses rise
- ✓Nationwide availability — the company states services are available in all 50 states through its provider network
- ✓Free overnight shipping — no additional shipping charges are advertised
- ✓Multiple payment options — supports financing such as Klarna, Afterpay, and Affirm
Things To Consider
Annual pricing requires longer commitments
The advertised $99 and $125 pricing are tied to longer-term plans. Monthly plans can cost significantly more.
Compounded medications are different from branded medications
Compounded semaglutide and compounded tirzepatide are not FDA-approved drug products themselves. Patients should understand that compounded medications are prepared by licensed pharmacies pursuant to individual prescriptions.
Not everyone qualifies
Eligibility depends on:
- ✗Medical history
- ✗BMI
- ✗Current medications
- ✗Provider assessment
Prescription approval is never guaranteed.
Compared to Embody at $69/month and Refills which focuses on refill management, Trimi differentiates with annual plan pricing starting at $99/month for semaglutide and a flat pricing model that doesn't increase as your dose titrates up. According to the FDA, semaglutide is approved for chronic weight management in adults with obesity or overweight with weight-related conditions.
Who Is Trimi Best For?
Trimi may be a good fit for people who:
- ✓Want lower-cost GLP-1 access
- ✓Prefer entirely online care
- ✓Want medication shipped to their home
- ✓Value straightforward pricing
- ✓Are comfortable committing to annual plans for maximum savings
Is Trimi Legit?
Based on publicly available information, Trimi appears to operate as a legitimate telehealth platform that partners with licensed clinicians and licensed 503A compounding pharmacies.
However, consumers should always:
- ✓Verify current pricing
- ✓Review provider credentials
- ✓Read all treatment disclosures
- ✓Understand compounded medication limitations
- ✓Consult their healthcare provider if they have complex medical conditions
Final Thoughts
Trimi positions itself as a budget-friendly GLP-1 provider focused on simplicity. The combination of semaglutide from $99/month, tirzepatide from $125/month, free overnight shipping, flat pricing, and nationwide access makes it an option worth considering for patients comparing telehealth weight loss providers.
Our Editorial Take
Pulling the threads together: Trimi's real edge isn't simply that it's cheap, it's that the flat-rate model keeps it cheap as your dose climbs — the point where a lot of “low starting price” programs quietly stop being cheap. Bundling medication, supplies, oversight, and free overnight shipping into one number keeps it legible, too. The honest condition attached is the one from the top: the best rates want a longer commitment, so this rewards the person ready to plan in blocks rather than dabble for a month.
The trade-offs are familiar for this category: the headline pricing is tied to longer commitments, and the programs use compounded medications that are not FDA-approved. If you understand the compounding distinction and are comfortable with an annual plan, Trimi is worth a look, confirm current pricing and terms at checkout before enrolling.
Trimi: Frequently Asked Questions
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Our editorial team’s top picks for this category.
Not sure Trimi is right for you? Compare it against our top-rated picks on our Best Weight Loss Providers list.
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