Trimi vs Fridays: GLP-1 Cost & Plans Compared
Trimi vs Fridays compared on price, medication format and commitment terms. See which GLP-1 programme fits, and what each actually costs over a year.
Quick Verdict
Editorial Take
Best Overall: Trimi, on cost. Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own.
Best for Budget: Trimi. Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own.
Best for Fast Approval: Both run fully online intake with licensed clinician review, so approval speed is unlikely to separate them. Trimi quotes shipping as included in the plan; Fridays quotes included in the plan.
At a Glance Comparison
| Feature | Trimi | Fridays |
|---|---|---|
| Semaglutide price | $99/month | $117/month |
| Tirzepatide price | Not published before intake | $198/month |
| Needle-free oral option | No | Yes |
| Brand-name medication | No | Yes |
| Insurance support | No | Yes |
| Shipping | Included in the plan | Included in the plan |
Who Should Choose Trimi
Choose Trimi if:
- ✓You want a sub-$100 entry price on semaglutide
- ✓You are comparing on a published semaglutide rate of $99/month
- ✓You accept the trade-off that tirzepatide pricing is not published as a single headline rate
Who Should Choose Fridays
Choose Fridays if:
- ✓You want a $0 membership with unlimited provider visits, dietitian and mental-health coaching included
- ✓You are comparing on a published semaglutide rate of $117/month
- ✓You want a needle-free oral option
- ✓You want FDA-approved brand-name medication, not only compounded
- ✓You accept the trade-off that the headline rates more than double if you pay month-to-month
Trimi Deep Dive
Trimi leads with a sub-$100 entry price on semaglutide. Semaglutide is published at $99/month. The honest caveat is that tirzepatide pricing is not published as a single headline rate.
How It Works
- Complete the online intake covering health history and weight goals
- A licensed clinician reviews your information and prescribes if appropriate
- Medication ships — included in the plan
- Continue with clinician support for dose adjustment
Medications Offered
- ✓Semaglutide from $99/month
Pricing
$99/month semaglutide. Included in the plan.
- ✓A sub-$100 entry price on semaglutide
- ✓Included in the plan
- ✗Tirzepatide pricing is not published as a single headline rate
- ✗Compounded medication is not an FDA-approved finished product
Fridays Deep Dive
Fridays leads with a $0 membership with unlimited provider visits, dietitian and mental-health coaching included. Semaglutide is published at $117/month, tirzepatide at $198/month. The honest caveat is that the headline rates more than double if you pay month-to-month.
How It Works
- Complete the online intake covering health history and weight goals
- A licensed clinician reviews your information and prescribes if appropriate
- Medication ships — included in the plan
- Continue with clinician support for dose adjustment
Medications Offered
- ✓Semaglutide from $117/month
- ✓Tirzepatide from $198/month
- ✓Needle-free oral tablet option
- ✓FDA-approved brand-name GLP-1 medication
Pricing
$117/month semaglutide, though the $117 semaglutide and $198 tirzepatide rates are annual-plan prices; month-to-month is $279 and $389. Included in the plan.
- ✓A $0 membership with unlimited provider visits, dietitian and mental-health coaching included
- ✓Included in the plan
- ✓Needle-free oral option available
- ✓Insurance support available
- ✗The headline rates more than double if you pay month-to-month
Honest Tradeoffs
Pricing
Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own.
Medication Types
Fridays offers FDA-approved brand-name medication as well as compounded; Trimi is compounded-only. Compounded products are not FDA approved and have not been through the trials the branded versions have, so this is the most consequential difference between these two.
Doctor Involvement
Both require review by a licensed U.S. clinician before dispensing, and neither is a subscribe-and-ship product. Ongoing support for dose titration is included at both.
Delivery Speed
Trimi: Included in the plan. Fridays: Included in the plan. In practice the gap between clinician review times usually matters more than the shipping estimate.
Subscription Model
Fridays's advertised rate is conditional — the $117 semaglutide and $198 tirzepatide rates are annual-plan prices; month-to-month is $279 and $389 — whereas Trimi's published rate does not require a prepaid term. Weigh the committed price against the flexible one.
Pricing Breakdown
| Aspect | Trimi | Fridays |
|---|---|---|
| Semaglutide, monthly | $99/month | $117/month |
| Tirzepatide, monthly | Not published before intake | $198/month |
| 6-month semaglutide total | $594 | $702 |
| 12-month semaglutide total | $1,188 | $1,404 |
| Commitment required for best rate | No | Yes |
What You Actually Pay Over 12 Months
Advertised starting prices are the least useful number in this comparison, so below is what each provider costs across a realistic course of treatment rather than on day one. Pricing verified July 30, 2026; confirm the final figure at enrollment, as offers change.
| Trimi | Fridays | |
|---|---|---|
| First month | $99/month | $117/month |
| 6-month total | $594 | $702 |
| 12-month total | $1,188 | $1,404 |
| Price includes | Medication, clinician review and ongoing dose support. Shipping: included in the plan. | Medication, clinician review and ongoing dose support. Shipping: included in the plan. |
| What can raise it | No prepaid term is required to reach the advertised rate. | The advertised rate is conditional — the $117 semaglutide and $198 tirzepatide rates are annual-plan prices; month-to-month is $279 and $389. |
Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own. Fridays's advertised rate is conditional — the $117 semaglutide and $198 tirzepatide rates are annual-plan prices; month-to-month is $279 and $389 — whereas Trimi's published rate does not require a prepaid term. Weigh the committed price against the flexible one. Fridays offers FDA-approved brand-name medication as well as compounded; Trimi is compounded-only. Compounded products are not FDA approved and have not been through the trials the branded versions have, so this is the most consequential difference between these two.
Medication Comparison
Semaglutide
Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own.
Tirzepatide
Tirzepatide pricing is not published by both providers, so the dual-agonist comparison cannot be made from public information. Ask at intake if tirzepatide is what you want.
Which Provider Offers What
Fridays offers a needle-free oral option; Trimi is injection-only. Fridays offers FDA-approved brand-name medication as well as compounded; Trimi is compounded-only. Compounded products are not FDA approved and have not been through the trials the branded versions have, so this is the most consequential difference between these two.
Results Expectations
Safety Considerations
Side Effects
Both carry the GLP-1 side-effect profile: nausea, vomiting, diarrhoea, constipation and abdominal discomfort, typically dose-related and most pronounced during titration. GLP-1 medications carry serious warnings including the risk of thyroid C-cell tumours and should not be used by anyone with a personal or family history of medullary thyroid carcinoma or MEN 2. Disclose your full history at intake.
Doctor Supervision
Both require review by a licensed U.S. clinician before dispensing and provide ongoing support for dose adjustment.
Prescription Requirement
Fridays offers FDA-approved brand-name medication as well as compounded; Trimi is compounded-only. Compounded products are not FDA approved and have not been through the trials the branded versions have, so this is the most consequential difference between these two.
How We Evaluated These Providers
We evaluated both providers based on the following criteria:
- ✓Published monthly pricing for each molecule, and the six and twelve-month totals that follow from it
- ✓Whether the advertised rate requires a prepaid term
- ✓Medication formats offered, including any needle-free option
- ✓Regulatory status: compounded against FDA-approved brand-name
- ✓Whether insurance can be used at all
- ✓Shipping as published by each provider
Final Verdict
Editorial Take
Best for Budget Users
Trimi. Trimi is $18/month cheaper on semaglutide, $216 across a year. That is small enough that it should not be the deciding factor on its own.
Best for Fast Results
Tied, and neither should claim otherwise. Same molecules, comparable clinician-led process; the pace of results depends on titration and adherence rather than the provider.
Best for Doctor Supervision
Comparable. Both require licensed clinician review before dispensing and include ongoing dose support.
Best Premium Experience
Trimi for a sub-$100 entry price on semaglutide; Fridays for a $0 membership with unlimited provider visits, dietitian and mental-health coaching included. Which reads as premium depends on whether you value the programme around the medication or the lowest number on the invoice.
Frequently Asked Questions
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