Is MEDVi QUAD a supplement?

No. MEDVi QUAD is a prescription-only compounded medication that requires clinician approval. It is not sold over the counter and should not be confused with herbal ED supplements.

How quickly does MEDVi QUAD work?

Because it is absorbed sublingually (under the tongue) rather than swallowed, many users report effects within 10–15 minutes. This is faster than most standard oral ED tablets, though individual timing varies based on health, dosage, and other factors.

Will MEDVi QUAD cause a constant erection?

No. MEDVi QUAD creates a response window, an erection requires natural sexual stimulation during that window. It does not cause automatic or prolonged erections (priapism risk is extremely low at prescribed doses but should be discussed with your clinician).

Does MEDVi QUAD interact with food?

Less so than standard oral tablets. Because it is absorbed under the tongue rather than through the digestive system, heavy or fatty meals have less impact on onset time and absorption compared to swallowed sildenafil or tadalafil pills.

What if I am not approved by the clinician?

If a licensed U.S. clinician reviews your intake and determines MEDVi QUAD is not appropriate for your health profile, no charge is applied. You only pay if a prescription is approved and dispensed.

How does MEDVi QUAD compare to Viagra?

Viagra (sildenafil) is a single-ingredient PDE5 inhibitor that takes 30–60 minutes orally to work and lasts 4–6 hours. MEDVi QUAD contains sildenafil plus three other active ingredients (Apomorphine, L-Citrulline, tadalafil) delivered sublingually, potentially working in 10–15 minutes with a 36-hour window. It is more expensive but offers a multi-mechanism approach.

How does MEDVi QUAD compare to Cialis?

Cialis (tadalafil) is a once-daily or as-needed oral tablet lasting up to 36 hours. MEDVi QUAD includes tadalafil as one of its four ingredients but adds Apomorphine (desire), L-Citrulline (blood flow), and sildenafil (firmness) in a single sublingual dose. It may suit men who want broader coverage than tadalafil alone.

Is MEDVi safe to use?

MEDVi QUAD is dispensed only after a licensed clinician reviews your medical history. It is not suitable for men taking nitrates, those with certain cardiovascular conditions, or those on contraindicated medications. Common side effects include headache, flushing, nasal congestion, and mild nausea. Always disclose your full medication list during the intake process.

Can I get MEDVi QUAD without a doctor visit?

There is no in-person visit required. MEDVi operates through a fully online telehealth platform. You complete a detailed medical questionnaire, a licensed U.S. clinician reviews it, and, if approved, medication is dispensed and shipped discreetly to your door.

Does insurance cover MEDVi QUAD?

MEDVi QUAD is a compounded medication and is generally not covered by standard insurance plans. Pricing is $114/month for 5 doses or $179/month for 10 doses, and includes the consultation, prescription, medication, and shipping — no hidden fees.

How does MEDVi QUAD compare to Rugiet Ready?

MEDVi QUAD and Rugiet Ready are two of the most comparable sublingual compounded ED medications on the market. Both share Sildenafil, Tadalafil, and Apomorphine for desire, in a sublingual format with rapid onset (10–15 minutes) and a 36-hour response window. MEDVi QUAD adds an L-Citrulline blood-flow booster on top of that shared formula, and is priced at $114/month for 5 doses or $179/month for 10 doses. Rugiet Ready uses a troche (sublingual wafer) rather than a liquid. The choice often comes down to delivery format and whether the extra L-Citrulline blood-flow support is worth the difference to you.

How does MEDVi QUAD compare to FeelGood QUAD?

Both MEDVi QUAD and FeelGood QUAD are 4-in-1 compounded ED formulas built around the same Apomorphine desire pathway, but the fourth ingredient differs. MEDVi QUAD pairs Apomorphine, Sildenafil, and Tadalafil with an L-Citrulline blood-flow booster, while FeelGood QUAD swaps L-Citrulline for Vardenafil, a third PDE5 inhibitor. Pricing differs too: FeelGood QUAD starts at $99/month and uses a sublingual tablet format, while MEDVi QUAD uses a liquid sublingual formula priced at $114/month for 5 doses or $179/month for 10 doses. Both are clinician-prescribed and delivered via telehealth.

Is MEDVi QUAD legitimate?

Yes. MEDVi QUAD is dispensed by a licensed U.S. compounding pharmacy and requires clinician approval before any prescription is processed. It is a legitimate prescription-only compounded medication, not a supplement or over-the-counter product. Compounded medications combine FDA-approved active ingredients into a custom formulation prepared by a licensed pharmacy. MEDVi operates through a regulated telehealth intake and does not dispense medication without clinical review.

What is the MEDVi QUAD dosage?

MEDVi QUAD dosage is determined by the prescribing clinician based on your health profile and intake responses. It is a liquid sublingual formula taken under the tongue before sexual activity. Dosing guidance, including the specific concentration of each of the four ingredients, is provided with your prescription and may be adjusted based on your response and tolerance. Do not self-adjust the dose without consulting your MEDVi clinician.

How do I cancel my MEDVi QUAD subscription?

MEDVi subscriptions can be cancelled by contacting MEDVi customer support directly. There is no long-term contract required, and the subscription is month-to-month. If you decide MEDVi QUAD is not right for you, you can cancel before the next billing cycle. Contact MEDVi through their website or the support email provided with your order confirmation.

Is MEDVi QUAD a scam?

No. Searches like "is MEDVi QUAD a scam" usually come from men who are wary of ED products sold online, but MEDVi QUAD is a prescription-only compounded medication dispensed by a licensed U.S. pharmacy only after a clinician reviews your intake. It is not an over-the-counter supplement or a fake-review "consumer reports" gimmick. The MEDVi QUAD reviews and complaints we have come across mostly concern price expectations and shipping timing, not product legitimacy, and you are only billed if a prescription is approved.

How much does MEDVi QUAD cost?

MEDVi QUAD pricing is straightforward: the 5-pack (a five-dose quad dose supply) costs $114, and the 10-pack costs $179, which lowers the per-dose price to about $17.90. That MEDVi QUAD cost includes the online consultation, the compounded prescription, discreet shipping, and ongoing clinical support, so the quad ED cost is all-inclusive rather than a per-item charge. There is no charge if the clinician does not approve you.

What are the most common MEDVi QUAD side effects?

The most commonly reported MEDVi QUAD side effects are mild and dose-related: headache, facial flushing, nasal congestion, and mild nausea (Apomorphine in particular can contribute to nausea in some users). Because the formula combines two PDE5 inhibitors with Apomorphine and L-Citrulline, you should disclose your full medication list during intake so the clinician can screen for interactions. MEDVi QUAD is not appropriate for men taking nitrates or those with certain cardiovascular conditions.

How many doses are in a bottle of QUAD?

The QUAD 5-pack contains 5 sublingual doses for $114/month, working out to roughly $22.80 each. The 10-pack contains 10 doses for $179/month, or about $17.90 each — a per-dose saving of around 21%. Which one you are approved for is a clinical and budget decision made during intake. Both are month-to-month with no partial refill if you run through your doses before the cycle ends.

What is the dosage for MEDVi QUAD, and is there an ingredients dosage list?

There is no published milligram list, because QUAD is compounded per patient rather than manufactured to a fixed strength. The pharmacy prepares your bottle at the Apomorphine, sildenafil, L-Citrulline, and tadalafil concentrations your reviewing clinician specified based on your intake, which means two men on the same plan can be on different strengths. The dosing sheet that ships with your order is the authoritative chart for your prescription, and any ingredient amounts quoted in forums or third-party listings reflect somebody else's script rather than a product specification.

How do you take MEDVi QUAD, and how long does it last?

Dispense the prescribed amount under your tongue and hold it there for about 60 to 90 seconds before swallowing what is left — swallowing immediately defeats the sublingual absorption that gives QUAD its 10 to 15 minute onset. Take it roughly 10 to 15 minutes before sexual activity, once in any 24-hour period, and never alongside another PDE5 inhibitor. The response window then runs up to about 36 hours thanks to the tadalafil component, which is a window in which an erection can occur with stimulation rather than a continuous erection.

ED Treatment Review

MEDVi QUAD Review 2026: Does MEDVi ED Really Work?

MEDVi QUAD puts four complementary ingredients — Apomorphine, Sildenafil, L-Citrulline, and Tadalafil — into a single sublingual liquid, pairing a desire pathway with a blood-flow booster and two proven PDE5 inhibitors.

4 active ingredients in one sublingual liquid dose
Onset in as little as 10–15 minutes; up to a 36-hour window
Clinician-reviewed; prescription only
No charge if the clinician does not approve you

9.2

Comprehensive 4-in-1 sublingual liquid

$114/mo (5 doses) · $179/mo (10 doses)

Prescription only — a licensed U.S. clinician decides if you are eligible

By Charly P. · Not medically reviewed

Updated August 2026 · Pricing last checked August 2026

4-in-1 sublingual formula
10–15 minute onset
Clinician-reviewed
No charge if not approved

Disclosure: ExploreTreatments.com may earn a commission if you begin treatment through links on this page, at no additional cost to you. This does not influence our editorial assessment.

Erectile dysfunction affects an estimated 30 million men in the U.S. and the treatment landscape has expanded well beyond the traditional “blue pill.” MEDVi QUAD is a clinician-prescribed MEDVi ED medication that puts four complementary ingredients — Apomorphine, Sildenafil, L-Citrulline, and Tadalafil — into a single sublingual (under-the-tongue) liquid. A four-in-one formula sounds obviously better, but more ingredients also means more cost and a wider side-effect surface — at $114/month for 5 doses ($179 for 10) it's a real step up from a generic. See our full Best ED Providers comparison list for how MEDVi QUAD ranks alongside other top options.

What Is MEDVi QUAD?

MEDVi QUAD is a telehealth-based, prescription-only compounded medication for erectile function in adult men — not a supplement, not sold over the counter. An online medical questionnaire is reviewed by a licensed U.S. clinician before any prescription is approved. What sets it apart from conventional ED pills is its four-ingredient sublingual-liquid formula: absorbed directly through tissue under the tongue instead of traveling through digestion, for a faster, more predictable onset.

Aimed at men who haven't found single-ingredient tablets fully satisfying — inconsistent timing, reduced effectiveness with food, or wanting a broader approach to sexual response.

Start Your Free Medical Evaluation at MEDVi →

Quick-Look Summary

Product Name	MEDVi QUAD
Product Type	Prescription-only compounded medication
Delivery Method	Sublingual liquid (under the tongue)
Prescription Required	Yes, online intake reviewed by a licensed U.S. clinician
Active Ingredients	Apomorphine, Sildenafil, L-Citrulline, Tadalafil
Onset Time	As little as 10–15 minutes (individual results vary)
Response Window	Up to 36 hours (no automatic erection)
Food Interaction	Less affected by meals vs. standard oral tablets
Starting Price	$114/month (5 doses) · $179/month (10 doses)
What's Included	Consultation, prescription, medication, discreet shipping, ongoing support
No-Approval Policy	No charge if clinician does not approve the prescription

Check Your Eligibility →

How It Works: The Sublingual Advantage

Standard ED tablets are swallowed and absorbed through the gut — slowed by food, particularly fatty meals. Sublingual delivery bypasses digestion entirely: active compounds pass directly into the bloodstream through the mucous membranes under the tongue.

In practice: faster onset (potentially 10–15 minutes), less variability with food, and a more consistent effect window. MEDVi QUAD creates a response window — an extended period during which an erection can occur naturally with sexual stimulation — rather than an automatic or constant erection.

MEDVi QUAD 4-in-1 formula: Apomorphine, Sildenafil, L-Citrulline, Tadalafil

The Four Active Ingredients: What Each One Does

MEDVi QUAD earns its name from the four active ingredients it contains, each targeting a different part of the sexual response:

Apomorphine — Desire	A dopamine receptor agonist working through the central nervous system, not primarily on blood vessels — supports the neurological and psychological side of arousal. MEDVi updated the QUAD formula to Apomorphine from its earlier PT-141 version.
Sildenafil — Firmness	The most widely recognized ED ingredient; enhances blood flow to penile tissue to support erection quality. Decades of clinical use give it one of the strongest track records in the category.
L-Citrulline — Rapid Flow	An amino acid the body converts to L-arginine to boost nitric oxide production, relaxing blood vessels and improving circulation — supports stronger, faster blood flow.
Tadalafil — Extended Duration	Best known for its long active window, up to 36 hours, compared to other PDE5 inhibitors — keeps the body responsive over an extended period, reducing pressure around strict timing.

Try the 4-in-1 Formula →

MEDVi QUAD Dosage Chart: What You Actually Get Per Bottle

Anyone searching for a “MEDVi QUAD dosage chart” is usually after one of two things: how many doses come in a bottle, or the exact milligram breakdown of the four ingredients. The first has a clean answer. The second does not exist in published form. QUAD arrives as a sublingual liquid on one of two monthly plans:

Plan	Doses per bottle	Price	Per dose	Typical use
QUAD 5-pack	5	$114/month
QUAD 10-pack	10	$179/month

Moving from five doses to ten cuts the per-dose price by roughly 21% — the only real volume discount on offer. Both prices are all-inclusive (consultation, compounded prescription, shipping, clinical support) and month-to-month, so the 5-pack is the sensible way to test response before the larger bottle.

Why the milligram breakdown isn't published

QUAD is compounded, not manufactured to a fixed SKU — a licensed pharmacy prepares each order at the concentrations your clinician specified from your intake. A generic sildenafil tablet can advertise 50 mg because every tablet is identical; QUAD cannot, because two patients on the same $114 plan may hold bottles at different strengths. The FDA does not review or approve compounded drug products for safety, effectiveness, or manufacturing quality the way it does finished commercial drugs — the individual actives have that history, the specific blend in your bottle does not.

Taking a dose correctly

✓Dispense the prescribed amount under the tongue and let it sit for 60–90 seconds before swallowing the remainder.
✓Time it roughly 10–15 minutes ahead of sexual activity. Tadalafil stretches the window toward 36 hours, so precision matters less.
✓One dose per 24 hours, no exceptions. Never combine QUAD with Viagra or Cialis.
✓Food interferes less than with swallowed tablets, but significant alcohol still works against you.
✓If the dose underperforms or side effects are unpleasant, raise it with your MEDVi clinician rather than adjusting on your own.

The Ordering Process

1.
Complete the Online Questionnaire
Fill out an online medical questionnaire — the kind of information a clinician needs to evaluate safety and appropriateness. No in-person visit required.
2.
Licensed Clinician Review
A licensed U.S. clinician reviews your responses. If MEDVi QUAD is not a good fit for your health profile, no charge is applied.
3.
Discreet Delivery
If approved, your compounded prescription is processed and shipped directly to your door in unmarked packaging, with ongoing clinical support included.

Review Prescribing Details & Check Eligibility →

Pros & Cons

Pros

Four-mechanism formula instead of a single ingredient
Sublingual delivery for faster, more consistent onset
Up to 36-hour response window reduces timing pressure
Clinician-reviewed and medically supervised
Discreet, plain-packaging home delivery
No charge if not approved

Cons

Requires a prescription and medical approval
Higher monthly cost than generic single-ingredient options
Not suitable for all health profiles
Limited long-term independent research on the specific combined formulation

Pricing & What's Included

MEDVi QUAD is available in two plans: $114/month for 5 doses ($22.80 per dose) or $179/month for 10 doses ($17.90 per dose) — both covering the online medical consultation, prescription processing, medication, free rush shipping, and ongoing clinical support. No charge is applied if clinician review finds you're not a good candidate. For a lower per-dose cost, compare DirectMax.

See MEDVi QUAD Pricing →

Who Should Consider MEDVi QUAD?

Good fit for men who've tried standard single-ingredient ED medications with inconsistent results, want a formula addressing both physical and psychological arousal, or prefer online telehealth over an in-person visit. Likely not the best starting point if you've never tried ED medication before (a lower-cost generic is a reasonable first step), have cardiovascular contraindications, or want the simplest, most affordable approach.

Who should NOT use MEDVi QUAD: men taking nitrates (nitroglycerin, isosorbide); men with certain cardiovascular conditions (recent heart attack, unstable angina, severe heart failure); men on alpha-blockers or certain antifungals/antibiotics; men with severe liver or kidney impairment; and men seeking an over-the-counter or herbal option. If any apply, MEDVi's intake clinician will not approve a prescription, and no charge is applied.

Find Out If MEDVi QUAD Is Right for You →

How We Scored MEDVi QUAD

Our 9.2/10 is a weighted mean of six categories, scored in August 2026 using the same criteria we apply to every ED provider. Where we could not verify a claim, the category is capped rather than given full marks.

How We Scored It

9.2

Comprehensive 4-in-1 sublingual liquid

Formula & effectiveness(25%)9.5

A coherent four-pathway design — desire (Apomorphine), firmness (sildenafil), blood flow (L-Citrulline), and duration (tadalafil) — in one sublingual dose.

Medical safeguards(20%)9.0

Licensed U.S. clinician reviews intake and screens contraindications before any prescription; no charge if not approved.

Service & support(15%)9.0

Bundled consultation, compounding, discreet shipping, and ongoing clinical support in one month-to-month plan.

Customer experience & evidence(15%)9.2

Strong user reports and a mature telehealth flow, though the specific compounded blend has limited independent long-term research.

Privacy & convenience(15%)9.5

Entirely online intake with discreet plain-packaging home delivery and no in-person visit.

Value & pricing(10%)8.5

A premium over generics, but all-inclusive; the 10-dose plan cuts per-dose cost by ~21% for frequent users.

The same weighted method is applied to every provider we score, so competitor ratings are comparable. See our best ED providers guide.

MEDVi QUAD vs Viagra vs Cialis, and the Compounded Field

Most men evaluating MEDVi QUAD are coming from one of two directions: they've already tried generic sildenafil (Viagra) or tadalafil (Cialis) and want something stronger, or they're new to ED treatment and comparing all options.

Feature	MEDVi QUAD	Viagra (Sildenafil)
Active Ingredients	4 (Apomorphine, Sildenafil, L-Citrulline, Tadalafil)	1 (Sildenafil)
Delivery	Sublingual liquid	Oral tablet
Onset Time	10–15 minutes	30–60 minutes
Duration Window	Up to 36 hours	4–6 hours
Food Effect	Minimal	Reduced with fatty meals
Mental Arousal Support	Yes (Apomorphine)	No
Monthly Cost	$114 (5 doses) · $179 (10 doses)	$20–$60 (generic)
Telehealth Included	Yes	Separate cost

The core difference is breadth. Viagra and Cialis are proven, affordable single-ingredient options, excellent first choices for most men. MEDVi QUAD targets men who have already tried PDE5 inhibitors and want faster onset, broader mechanism coverage, or more flexibility in timing.

MEDVi QUAD vs. DirectMax

Feature	MEDVi QUAD	DirectMax
Formula	4-in-1 (Apomorphine + Sildenafil + L-Citrulline + Tadalafil)	Triple-action (Apomorphine + Sildenafil + Tadalafil)
Delivery Format	Sublingual liquid (under the tongue)	Rapid dissolve tablet
Onset Time	10–15 minutes	~15 minutes
Duration Window	Up to 36 hours	Up to 36 hours
Starting Price	$114/mo (5 doses) · $179/mo (10 doses)	From $7.45/dose
Blood-Flow Booster	L-Citrulline	None
Best For	Men wanting the most comprehensive multi-pathway formula	Men seeking a lower per-dose cost with triple-action coverage

Read our full DirectMax by DirectMeds review →

MEDVi QUAD is not the only 4-in-1 compounded ED formula on the market:

Rugiet Ready combines Sildenafil, Tadalafil, and Apomorphine in a sublingual troche (wafer) — the same desire pathway MEDVi QUAD now uses, but with no L-Citrulline blood-flow booster.
FeelGood QUAD is a 4-in-1 sublingual tablet using Apomorphine, Vardenafil, Sildenafil, and Tadalafil, swapping MEDVi QUAD's L-Citrulline for a third PDE5 inhibitor.
BraveRX is a 3-in-1 oral dissolving tablet with a strong emphasis on the Apomorphine arousal pathway.
QMAX by BetterMe Rx is the closest liquid alternative, stacking three PDE5 inhibitors plus Apomorphine.
For a couples-focused five-ingredient tablet that adds oxytocin and B12, see LuckyRx Lucky WOW.

Top-rated ED providers we recommend:

Recommended Providers

Our editorial team’s top picks for this category.

9.9★Visit Site →

9.8★Visit Site →

9.7★Visit Site →

Safety, Side Effects & Medical Oversight

MEDVi QUAD is only dispensed after a licensed clinician reviews your intake. Because it's a compounded medication, prepared specifically to combine these four active ingredients, it requires a full and honest medical history from the user.

It is not appropriate for everyone. Men with certain cardiovascular conditions, those taking nitrates, or users on contraindicated medications should not use MEDVi QUAD. Potential side effects, which vary by individual and dose, may include headaches, facial flushing, mild nausea, nasal congestion, and temporary dizziness. Many side effects, when they occur, are dose-related and can be managed with guidance from a healthcare provider.

Frequently Asked Questions

9.9★Visit Site →

9.8★Visit Site →

9.7★Visit Site →

Still Have Questions? Start Your Evaluation →

Final Verdict

Our Editorial Take

Pulling it together: MEDVi QUAD is a carefully built, clinician-managed formula rather than a marketing exercise. Combining Apomorphine, sildenafil, L-Citrulline, and tadalafil to cover desire, firmness, blood flow, and duration in one sublingual dose is a genuinely coherent design, and the under-the-tongue delivery is a practical win for anyone tired of timing a pill around a meal. The part I'd underline before you buy: it's not magic, and the premium over a generic is real. If you've never taken an ED medication, this is a lot of firepower for a problem a $20 script might solve on its own — start simpler and step up only if you need to. The men who get the most out of MEDVi are the ones who've already found single-ingredient tablets wanting; for them the broader formula is exactly the point, and it's a legitimate option under medical supervision. Overall: 9.2/10.

4-in-1 sublingual formula · $114/mo (5 doses)

Get Started with MEDVi QUAD Today →

No charge if not approved · Cancel anytime · Discreet shipping

Medical Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before starting or changing any prescription treatment. Individual results may vary.

Disclosure: ExploreTreatments.com may earn a commission if you begin treatment through links on this page, at no additional cost to you. This does not influence our editorial assessment.

About This Review

Researched by: Charly P., Founder and Telehealth Researcher
Last Reviewed: August 2026
Disclosure: ExploreTreatments may receive compensation from partner links. This does not influence our editorial process. Read our editorial policy.

References

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Medical Disclaimer: The content on this site is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider for medical questions, treatment decisions, or emergency care. Do not disregard professional medical advice or delay seeking it based on information found here.