Best Weight Loss Injections in Canada

Weight Loss Medication in Canada: The Complete 2026 Guide

How online GLP-1 care works in Canada

The route is entirely remote. You complete an online health intake, a licensed Canadian clinician reviews your history and eligibility, and if a GLP-1 is appropriate the prescription goes to a licensed Canadian pharmacy and ships to your door. No referral, no in-person appointment, and — at every provider ranked here — no requirement to have insurance.

What the remote route does not remove is the clinical work. GLP-1 therapy is a titration: you start low, step up over several weeks, and the dose is adjusted around how you tolerate it. A program that ships medication without managing that escalation is selling you a box, not care — which is why clinical support is one of the six things we weigh below.

What is approved in Canada

Health Canada has approved a compact set of GLP-1 medications for weight management and diabetes, and its Drug Product Database is the authoritative list of what a Canadian clinician can prescribe. Everything on this page is drawn from it.

The average weight-loss figures above come from the manufacturers' pivotal trials, not from our own data. The STEP 1 trial of semaglutide 2.4mg reported a mean reduction of roughly 15% of body weight over 68 weeks alongside lifestyle intervention — which is the number Wegovy is marketed on, and a useful reminder that every result in that column was produced with diet and activity support, not by the injection alone.

Generic semaglutide, and why Canada has it first

Canada's semaglutide patent situation diverged from the rest of the G7, and in 2025 Health Canada approved generic versions from two manufacturers. The effect on price was immediate: the same active ingredient, on the same weekly schedule, from around $149 a month including the prescription and delivery, against $200–$450 for brand-name Ozempic.

For most readers optimising on cost, this is the answer — and it is the reason a Canadian comparison page looks different from an American one. Our generic semaglutide guide breaks down Plosbrio and Poviztra and what each provider charges for them, and the Canadian cost guide prices a full year across every option on this page.

Why there are no compounded GLP-1s here

If you have compared against our US weight loss provider comparison, the cheap compounded semaglutide and tirzepatide programs that dominate that market are conspicuously absent here. Health Canada restricts the compounding of drugs that are commercially available in approved form, and semaglutide and tirzepatide both are — so a Canadian clinic cannot legally prepare or sell a compounded version for weight loss.

A site advertising compounded GLP-1s to Canadians is either shipping from outside the country or misdescribing what it sells; neither is a risk worth taking with an injectable. The approved generic exists precisely so the low-cost route does not have to be an unapproved one.

Cost, coverage and what insurance does

Three funding routes exist in Canada, and most readers of this page end up on the third:

Two costs are easy to miss when comparing headline prices. The first is the consultation: Felix advertises $0, and Direct Meds includes the visit in its program price. The second is dose escalation — the monthly figure at the starting dose is not the figure at the maintenance dose, so price the dose you expect to reach rather than the one you begin on. Provincial coverage rules differ as well; our Ontario guide covers the ODB limited-use rules in detail.

Who qualifies, and what to expect

Eligibility criteria are broadly consistent across Canadian clinics, and the clinician reviewing your intake makes the final call:

• Generally a BMI of 30 or above, or 27 and above with a weight-related condition such as type 2 diabetes or hypertension.
• A personal or family history of medullary thyroid carcinoma or MEN2 rules out GLP-1 therapy entirely.
• Prior pancreatitis, active gallbladder disease, severe gastrointestinal disease and pregnancy all require careful clinical review.
• Nausea, constipation and reflux are common during titration and usually ease as the dose settles — tell your clinician rather than stopping unilaterally.
• Expect a titration schedule of roughly 4 to 20 weeks depending on the medication before you reach the maintenance dose.

How the two providers compare

Felix Health takes the top spot on breadth and access. It is the most recognised digital health brand in Canada, the initial consultation is $0, treatment prices have come down sharply, and it prescribes the full brand-name slate — Ozempic, Wegovy and Mounjaro — with ongoing follow-up and free delivery. Its limit is geographic: Quebec and the territories are not served, and brand-name pricing sits well above the generic.

Direct Meds ranks second, with brand-name injectable programs from $99 a month, the telehealth visit and prescription included, and free 1–2 day shipping. If price is the deciding factor and you are open to generic semaglutide rather than a brand-name medication, see our generic semaglutide guide — that page tracks the confirmed generic providers separately from the brand-name comparison here.

If you want the same comparison narrowed to your province or situation, we run dedicated pages for Ontario, British Columbia, Alberta, men, women and seniors. Felix Health also treats ED, compared on our Canadian ED page.