{"total":10,"last_updated":"2026-05-20","treatments":[{"name":"GLP-1 Weight Loss","slug":"weight-loss","category":"Weight Management","url":"https://www.exploretreatments.com/weight-loss","reviews_url":"https://www.exploretreatments.com/weight-loss/reviews","guides_url":"https://www.exploretreatments.com/weight-loss/guides","cost_url":"https://www.exploretreatments.com/weight-loss/cost","status":"live","description":"GLP-1 receptor agonist medications (semaglutide, tirzepatide) prescribed by licensed clinicians via telehealth for medically supervised weight loss.","key_benefits":["Clinically proven weight reduction of 10–22% body weight","Reduced appetite and improved satiety signaling","Improved metabolic markers including blood sugar and blood pressure","Convenient once-weekly injectable or daily oral formats","Supervised by licensed physicians with ongoing monitoring"],"medications":[{"name":"Semaglutide (Wegovy/Ozempic)","type":"Injectable GLP-1","format":"Weekly subcutaneous injection"},{"name":"Tirzepatide (Zepbound/Mounjaro)","type":"Dual GIP/GLP-1","format":"Weekly subcutaneous injection"},{"name":"Oral Semaglutide (Rybelsus/Oral GLP-1)","type":"Oral GLP-1","format":"Daily oral tablet/pill"}],"common_side_effects":["Nausea","Vomiting","Diarrhea","Constipation","Injection site reactions","Fatigue"],"serious_side_effects":["Pancreatitis","Gallbladder disease","Thyroid tumors (rare)","Severe allergic reactions"],"typical_eligibility":"BMI ≥30, or BMI ≥27 with at least one weight-related health condition (type 2 diabetes, hypertension, high cholesterol)","contraindications":["Personal/family history of MTC or MEN2","Pregnancy","Severe renal impairment","Active pancreatitis"],"pricing_range":"Compounded: $150–$400/month | Branded: $900–$1,400/month (without insurance)","insurance_coverage":"Branded versions may be covered with prior authorization; compounded generally not covered","state_availability":"Available in most US states; some restrictions on compounded versions","top_providers":[{"name":"Willow","url":"https://www.exploretreatments.com/weight-loss/reviews/willow"},{"name":"Eden","url":"https://www.exploretreatments.com/weight-loss/reviews/eden"},{"name":"Ro Body","url":"https://www.exploretreatments.com/weight-loss/reviews/ro"},{"name":"TrimRx","url":"https://www.exploretreatments.com/weight-loss/reviews/trimrx"}],"faqs":[{"question":"How much weight can I lose with GLP-1 medications?","answer":"Clinical trials show 10–22% average body weight loss over 68 weeks with lifestyle changes. Individual results vary based on dose, adherence, and metabolic factors."},{"question":"Do I need a prescription for GLP-1 weight loss medications?","answer":"Yes. Semaglutide and tirzepatide require a valid prescription from a licensed clinician after a medical evaluation."},{"question":"Are compounded GLP-1 medications safe?","answer":"Compounded semaglutide and tirzepatide should come from 503B-registered outsourcing facilities. Quality varies; always verify pharmacy credentials."}],"last_reviewed":"2026-05-20"},{"name":"Semaglutide","slug":"semaglutide","category":"Weight Management","url":"https://www.exploretreatments.com/weight-loss","status":"live","description":"Semaglutide is a GLP-1 receptor agonist approved by the FDA for chronic weight management (Wegovy) and type 2 diabetes (Ozempic). It works by mimicking GLP-1 hormones to reduce appetite and slow gastric emptying.","key_benefits":["Average 15% body weight loss in clinical trials","Once-weekly injectable with self-administration","FDA-approved for weight management (Wegovy)","Also improves cardiovascular risk markers","Available as compounded option for lower cost"],"medications":[{"name":"Wegovy","type":"Brand-name semaglutide","indication":"Weight management","approval":"FDA-approved"},{"name":"Ozempic","type":"Brand-name semaglutide","indication":"Type 2 diabetes (off-label for weight loss)","approval":"FDA-approved"},{"name":"Rybelsus","type":"Oral semaglutide","indication":"Type 2 diabetes","approval":"FDA-approved"},{"name":"Compounded semaglutide","type":"Compounded","indication":"Weight management","approval":"Not FDA-approved; requires 503B pharmacy"}],"dosing":"Titrated from 0.25mg/week to maintenance dose of 2.4mg/week (Wegovy) over 16–20 weeks","common_side_effects":["Nausea","Vomiting","Diarrhea","Constipation","Abdominal pain","Headache"],"typical_eligibility":"BMI ≥30 or BMI ≥27 with weight-related comorbidity; no personal/family history of thyroid cancer","pricing_range":"Compounded: $150–$350/month | Branded Wegovy: $1,000–$1,400/month","last_reviewed":"2026-05-20"},{"name":"Tirzepatide","slug":"tirzepatide","category":"Weight Management","url":"https://www.exploretreatments.com/weight-loss","status":"live","description":"Tirzepatide is a dual GIP/GLP-1 receptor agonist (the first of its class) approved by the FDA as Zepbound for weight management and Mounjaro for type 2 diabetes. It produces greater average weight loss than semaglutide alone.","key_benefits":["Up to 22% average body weight loss in SURMOUNT-1 trial","Greater efficacy than semaglutide in head-to-head comparisons","Once-weekly injectable format","FDA-approved as Zepbound for weight management","Dual-agonist mechanism targeting both GIP and GLP-1 receptors"],"dosing":"Titrated from 2.5mg/week to maximum 15mg/week over 20 weeks","common_side_effects":["Nausea","Diarrhea","Vomiting","Constipation","Decreased appetite"],"typical_eligibility":"BMI ≥30 or BMI ≥27 with weight-related comorbidity","pricing_range":"Compounded: $200–$450/month | Branded Zepbound: $1,000–$1,400/month","last_reviewed":"2026-05-20"},{"name":"Oral GLP-1","slug":"oral-weight-loss-glp1","category":"Weight Management","url":"https://www.exploretreatments.com/oral-weight-loss-glp1","reviews_url":"https://www.exploretreatments.com/oral-weight-loss-glp1/reviews","status":"live","description":"Oral GLP-1 medications include oral semaglutide (Rybelsus) and emerging oral tirzepatide formulations. These offer a needle-free alternative for patients who prefer not to self-inject.","key_benefits":["No injections required — oral tablet or capsule format","GLP-1 mechanism for appetite suppression and weight loss","FDA-approved oral semaglutide (Rybelsus) available","Emerging oral tirzepatide formulations in development","Convenient daily dosing for some patients"],"common_side_effects":["Nausea","Diarrhea","Abdominal pain","Decreased appetite"],"typical_eligibility":"Same as injectable GLP-1 programs; clinician assessment required","pricing_range":"$150–$500/month depending on formulation and provider","last_reviewed":"2026-05-20"},{"name":"Testosterone Replacement Therapy (TRT)","slug":"TRT-treatments","category":"Men's Health","url":"https://www.exploretreatments.com/TRT-treatments","reviews_url":"https://www.exploretreatments.com/TRT-treatments/reviews","guides_url":"https://www.exploretreatments.com/TRT-treatments/guides","cost_url":"https://www.exploretreatments.com/TRT-treatments/cost","status":"live","description":"Testosterone Replacement Therapy (TRT) is a medically supervised treatment for men with clinically confirmed low testosterone (hypogonadism). Delivered via telehealth with lab monitoring and ongoing physician oversight.","key_benefits":["Restored energy, libido, and mood","Improved muscle mass and body composition","Better sleep quality and cognitive function","Reduced fatigue associated with low T","Medically supervised with regular lab monitoring"],"administration_routes":["Intramuscular injections","Subcutaneous injections","Topical gels/creams","Patches","Oral testosterone (Jatenzo)","Pellets"],"typical_eligibility":"Adult men with testosterone <300 ng/dL on at least two morning tests, with symptoms of hypogonadism","contraindications":["Active prostate/breast cancer","Severe sleep apnea (untreated)","Desire for fertility (may reduce sperm count)","Severe erythrocytosis"],"lab_requirements":["Baseline: Total T, Free T, LH, FSH, PSA, CBC, metabolic panel","Ongoing: Total T, CBC (hematocrit monitoring), PSA annually"],"pricing_range":"$100–$350/month depending on treatment type and provider","common_side_effects":["Acne","Injection site reactions","Elevated red blood cell count","Sleep apnea worsening","Testicular atrophy","Mood changes"],"top_providers":[{"name":"Maximus","url":"https://www.exploretreatments.com/TRT-treatments/reviews/maximus"},{"name":"Defy Medical","url":"https://www.exploretreatments.com/TRT-treatments/reviews/defy-medical"}],"faqs":[{"question":"How long does TRT take to work?","answer":"Most men notice improvements in energy and mood within 3–6 weeks. Libido improvements typically occur within 3–6 weeks. Full body composition changes take 3–6 months."},{"question":"Is TRT permanent?","answer":"TRT is often long-term but not necessarily permanent. Stopping TRT will cause testosterone levels to decline back to previous levels. Some men use TRT long-term; others cycle on/off."},{"question":"Does TRT cause infertility?","answer":"TRT can suppress natural sperm production. Men desiring fertility should discuss options with a urologist or reproductive endocrinologist before starting TRT."}],"last_reviewed":"2026-05-20"},{"name":"Hormone Replacement Therapy (HRT) for Women","slug":"hrt-providers","category":"Women's Health","url":"https://www.exploretreatments.com/hrt-providers","reviews_url":"https://www.exploretreatments.com/hrt-providers/reviews","guides_url":"https://www.exploretreatments.com/hrt-providers/guides","status":"live","description":"Hormone Replacement Therapy (HRT) for women addresses menopausal and perimenopausal symptoms by supplementing declining estrogen and/or progesterone levels. Telehealth providers offer convenient access to licensed clinicians who can prescribe and monitor HRT.","key_benefits":["Relief from hot flashes, night sweats, and vasomotor symptoms","Improved sleep quality and mood stability","Reduced vaginal dryness and painful intercourse","Bone density protection against osteoporosis","Improved cognitive function and energy levels"],"treatment_types":[{"name":"Estrogen therapy (ET)","indication":"For women without a uterus"},{"name":"Combined estrogen-progesterone therapy (EPT)","indication":"For women with a uterus"},{"name":"Bioidentical HRT (BHRT)","indication":"Customized compounded formulations"},{"name":"Vaginal estrogen","indication":"Localized genitourinary symptoms"}],"typical_eligibility":"Perimenopausal or menopausal women with bothersome symptoms; no history of hormone-sensitive breast cancer, blood clots, or active liver disease","contraindications":["History of hormone-sensitive breast cancer","Unexplained vaginal bleeding","Active blood clots","Severe liver disease","History of endometrial cancer"],"pricing_range":"$50–$250/month depending on HRT type and provider","common_side_effects":["Breast tenderness","Bloating","Mood changes","Headaches","Irregular spotting"],"faqs":[{"question":"Is HRT safe?","answer":"Modern HRT is considered safe for most healthy menopausal women under 60 or within 10 years of menopause onset. Risks vary by individual health history, HRT type, and duration of use."},{"question":"What is bioidentical HRT?","answer":"Bioidentical hormones have the same molecular structure as hormones produced naturally in the body. FDA-approved bioidentical hormones (e.g., Estrace, Prometrium) are available, as well as custom compounded bioidentical preparations."}],"last_reviewed":"2026-05-20"},{"name":"Erectile Dysfunction (ED) Care","slug":"best-ed-providers","category":"Men's Health","url":"https://www.exploretreatments.com/best-ed-providers","reviews_url":"https://www.exploretreatments.com/best-ed-providers/reviews","guides_url":"https://www.exploretreatments.com/best-ed-providers/guides","status":"live","description":"Online ED care provides convenient, discreet access to licensed physicians who can diagnose erectile dysfunction and prescribe appropriate treatments including PDE5 inhibitors (sildenafil, tadalafil) and newer options.","key_benefits":["Discreet, private consultations without in-person visits","FDA-approved medications (sildenafil, tadalafil, vardenafil)","Same-day prescriptions often available","Generic options at significantly lower cost than branded","Ongoing follow-up and dose adjustment"],"medications":[{"name":"Sildenafil (Viagra)","type":"PDE5 inhibitor","duration":"4–6 hours","onset":"30–60 minutes"},{"name":"Tadalafil (Cialis)","type":"PDE5 inhibitor","duration":"Up to 36 hours","onset":"30 minutes"},{"name":"Vardenafil (Levitra)","type":"PDE5 inhibitor","duration":"4–5 hours","onset":"25–60 minutes"},{"name":"Avanafil (Stendra)","type":"PDE5 inhibitor","duration":"6 hours","onset":"15–30 minutes"},{"name":"Tri-Mix/Bi-Mix (compounded)","type":"Intracavernosal injection","duration":"Varies","onset":"5–20 minutes"}],"typical_eligibility":"Adult men with ED symptoms; cardiovascular screening required; nitrates and certain medications are contraindicated","contraindications":["Nitrate medications (absolute contraindication)","Severe cardiovascular disease","Recent heart attack or stroke (within 6 months)","Severe liver impairment"],"pricing_range":"Generic sildenafil/tadalafil: $20–$60/month | Branded: $300–$600/month","faqs":[{"question":"Is online ED treatment safe?","answer":"Yes, when provided by licensed clinicians who properly screen for contraindications. The key is ensuring cardiovascular screening and medication interaction checks are performed."},{"question":"How quickly does sildenafil work?","answer":"Sildenafil typically works within 30–60 minutes and lasts 4–6 hours. Taking with a high-fat meal may delay absorption by 30–60 minutes."}],"last_reviewed":"2026-05-20"},{"name":"NAD+ Therapy","slug":"NAD-treatments","category":"Wellness","url":"https://www.exploretreatments.com/NAD-treatments","reviews_url":"https://www.exploretreatments.com/NAD-treatments/reviews","guides_url":"https://www.exploretreatments.com/NAD-treatments/guides","status":"live","description":"NAD+ (Nicotinamide Adenine Dinucleotide) therapy involves supplementing declining NAD+ levels through various delivery methods. NAD+ plays a central role in cellular energy production and DNA repair.","key_benefits":["Potential improvement in energy and cellular metabolism","Supports DNA repair mechanisms","May improve cognitive function and mental clarity","Anti-aging properties under investigation","Convenient at-home delivery options (injections, nasal spray)"],"delivery_methods":[{"name":"IV Infusion","setting":"Clinic-based","duration":"2–4 hours per session"},{"name":"Subcutaneous injection","setting":"At-home self-injection","frequency":"Daily or as prescribed"},{"name":"Nasal spray","setting":"At-home","frequency":"Daily"},{"name":"Oral supplements","setting":"At-home","frequency":"Daily (lower bioavailability)"}],"evidence_quality":"Emerging — preclinical evidence is strong; human clinical trials are ongoing. Benefits are plausible but not yet definitively established in large-scale RCTs.","pricing_range":"At-home: $150–$400/month | IV infusions: $200–$700 per session","faqs":[{"question":"Does NAD+ therapy actually work?","answer":"Evidence is promising but preliminary in humans. Animal studies show strong results. Many patients report subjective improvements in energy and cognition, but large-scale controlled human trials are still underway."},{"question":"What is the best way to take NAD+?","answer":"IV infusion achieves the highest bioavailability but requires clinic visits. Subcutaneous injections offer high bioavailability with at-home convenience. Nasal spray is convenient and well-tolerated. Oral forms have lower bioavailability."}],"last_reviewed":"2026-05-20"},{"name":"Sermorelin","slug":"best-sermorelin-providers","category":"Wellness / Anti-Aging","url":"https://www.exploretreatments.com/best-sermorelin-providers","status":"live","description":"Sermorelin is a growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to produce and release growth hormone. Used in anti-aging and wellness contexts.","key_benefits":["Stimulates natural growth hormone production","Potential improvements in body composition","May improve sleep quality","Supports muscle recovery and lean mass","Lower risk profile than direct HGH administration"],"typical_eligibility":"Adults with symptoms of growth hormone deficiency; clinician evaluation required","pricing_range":"$150–$400/month depending on dosing protocol and provider","last_reviewed":"2026-05-20"},{"name":"Menopause Care","slug":"hrt-providers","category":"Women's Health","url":"https://www.exploretreatments.com/hrt-providers","status":"live","description":"Comprehensive menopause care via telehealth addresses physical and emotional symptoms of perimenopause and menopause through evidence-based treatments including HRT, non-hormonal options, and lifestyle support.","symptoms_addressed":["Hot flashes","Night sweats","Vaginal dryness","Sleep disturbances","Mood changes","Cognitive changes","Bone density loss","Sexual dysfunction"],"treatment_options":["HRT (estrogen, progesterone)","Non-hormonal medications (SSRIs, SNRIs, gabapentin)","Vaginal estrogen","Lifestyle modifications","Cognitive behavioral therapy for menopause"],"last_reviewed":"2026-05-20"}]}